---
product_id: 172643900
title: "Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract - 30-Day Supply"
brand: "vetsmart formulas"
price: "€ 132.41"
currency: EUR
in_stock: true
reviews_count: 8
category: "Vet Smart Formulas"
url: https://www.desertcart.sk/products/172643900-critical-immune-defense-for-dogs-and-cats-supports-normal-cell
store_origin: SK
region: Slovakia
---

# Patented white turmeric extract 4 potent medicinal mushrooms Immune system booster Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract - 30-Day Supply

**Brand:** vetsmart formulas
**Price:** € 132.41
**Availability:** ✅ In Stock

## Summary

> 🦴 Boost your pet’s vitality with nature’s immune champions!

## Quick Answers

- **What is this?** Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract - 30-Day Supply by vetsmart formulas
- **How much does it cost?** € 132.41 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.sk](https://www.desertcart.sk/products/172643900-critical-immune-defense-for-dogs-and-cats-supports-normal-cell)

## Best For

- vetsmart formulas enthusiasts

## Why This Product

- Trusted vetsmart formulas brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Inflammation Defense:** Supports healthy inflammatory response for resilient pets
- • **Clean & Premium Quality:** Made in the USA with no artificial fillers or flavors
- • **Mushroom Powerhouse Blend:** Turkey Tail, Reishi, Shiitake & Maitake unite for cellular vitality
- • **All-Age, All-Breed Support:** Perfect for puppies, kittens, and senior companions alike
- • **Veterinarian-Formulated Immunity:** Scientifically crafted to strengthen your pet’s natural defenses

## Overview

Critical Immune Defense is a vet-developed, 30-day powder supplement for dogs and cats that combines four powerful mushrooms with patented white turmeric extract to support normal cell growth, reduce inflammation, and enhance immune resilience. Ideal for pets of all ages and breeds, it promotes long-term health and vitality using premium, natural ingredients made in the USA.

## Description

desertcart.com : Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract - 30-Day Supply : Pet Supplies

Review: I AM BACK TO BUY MORE! - Update: We have only one bottle of powder left, so I'm reordering. I still have my grand-dog, Gus, on this supplement, and he is still running and chasing the ball during play time. My son is a firm believer in this product, and so am I. I have my younger female dogs on it as well. It is costly, but when I consider eventual vet bills that might be prevented if dogs have this stuff all their lives, I prefer to keep them healthy now so we can avoid some of the absurdly expensive health issues later in life. I can't seem to leave a vet's office without a three-hundred-dollar bill, and that is for basically nothing. Anything serious can be one or two thousand or much higher. It strikes me as being smarter to try to prevent serious issues for as long as we can, and in the meantime, our three dogs are happy, healthy, and enjoying a good playtime with the ball every day. At mealtime, they don't hesitate to eat, and if we didn't get all the powder mixed in well with their food, they lick the bowls clean, getting every last bit of the supplement. After eating, they circle around to see if another dog left any traces of anything in the bowl, and if one misses some of this supplement powder, they lick it up. So it doesn't taste icky to my dogs. I researched the ingredients and am thinking about finding a human version of this stuff. I think the company has done a stellar job of researching what will actually help our dogs--and I know there are human supplements, made of approximately the same stuff, that reviewers rave about. I'm 76, but who knows? If I get the same nutrients, maybe I'll be more energetic as well and help chase that darned ball! First post: I got this, despite the price, just to see. My son has a seven-year-old Aussie who was no longer wanting to chase the ball, who stood back and just didn't seem to care about playing anymore with our two younger dogs. It was so sad to see! He is still so young. I remembered reading about Critical Immune Defense and seeing good reviews. So, despite the cost, I decided to order some. I gave my grand-dog, Gus, his three scoops (he's a larger dog than my girls, so they only get two) on his food per meal for three days. (I did mention to my son that I was doing so. It is his dog, after all.) So we sailed along for three days, and all of a sudden, my grand-dog, Gus, began bursting forward to chase the ball and play. He was like a puppy again, all excited and racing around. It made my heart swell, because I was thinking, "That Stuff is actually Working!" My son said nothing. So, I thought, okay, fine. I can do without spending all that money on snake poison, even though I believed I was seeing a huge change in my grand-dog, Gus. My thought was, "I saw a placebo effect. I convinced myself, so I believed in the hype." My son didn't mention seeing a difference. So, hello, the stuff is expensive. I decided not to buy anymore. I'm not an idiot. So a few days later, my son calls. (We live on the same property, so our dogs all eat together.) "Mom, are you still giving Gus his supplement?" I thought I had messed up, because I wasn't giving him anything. I was, like, WHAT supplement? My son was, like, that stuff that started making him play like a puppy again! He was very upset that I had stopped giving his dog the CID. He would have been eagerly willing to continue the supplement at his own cost and trouble! The difference in the dog was huge. I popped back, saying that he'd never said a word about how it changed Gus. Why would I continue giving it to him? The stuff is costly! (I hope the company can shave away at their overhead to reduce the cost of product. ) Bottom line, this stuff DOES work! It isn't about buying it and only thinking it works. It truly does, and our Gus is suddenly running and playing like a much younger dog. It has given him a new lease on life. I have decided to also give it to my two younger dogs, hopefully as a preventative supplement. And, hello, I'm researching to find a human-grade supplement with mostly the same ingredients. I could stand a boost energy to make me feel better, too!
Review: Healthy pets - Very good product for my pets.

## Features

- IMPORTANT STATISTIC - According to the American Veterinary Cancer Society, 47% of dogs and 32% of cats over the age of 10 are diagnosed with some form of cancer.
- POWERFUL IMMUNE SYSTEM SUPPORT FOR DOGS & CATS - Veterinarian-developed formula that strengthens your pet’s immune system to help maintain health and support defense against common challenges. Ideal for dogs and cats of all breeds and ages, from active puppies and kittens to senior pets.
- PROMOTES NORMAL CELL GROWTH - Unique blend of four powerful mushrooms, concentrated white turmeric extract, and vitamins to boost Natural Killer (NK) and T-Helper cells; supports your pet’s long-term health by helping good cells eliminate abnormalities.
- REDUCES INFLAMMATION & SUPPORTS IMMUNE RESILIENCE - Formulated to promote a healthy inflammatory response and strengthen your pet’s natural defenses. Supports the body’s protective barrier against everyday environmental stressors that can challenge immune function. Rich in free-radical fighters to support cellular protection, enhance vitality, and promote a longer, healthier life for your pet.
- VET-FORMULATED, PREMIUM QUALITY – MADE IN THE USA Crafted by scientists and veterinarians using natural ingredients — free from artificial flavors, colors, or fillers — and produced under strict quality standards for results you can trust.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Brand | VetSmart Formulas |
| Customer Reviews | 4.3 out of 5 stars 1,708 Reviews |
| Dog Breed Size | Large |
| Flavor | Hypo-allergenic Chicken Flavor |
| Item Form | Powder |
| Item Weight | 6.34 Ounces |
| Specific Uses For Product | Immune Defense |

## Product Details

- **Brand:** VetSmart Formulas
- **Dog Breed Size:** Large
- **Flavor:** Hypo-allergenic Chicken Flavor
- **Item Form:** Powder
- **Item Weight:** 6.34 Ounces

## Images

![Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract - 30-Day Supply - Image 1](https://m.media-amazon.com/images/I/71EfFkLqawL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: Question for the manufacturer.  Does this contain the fruiting bodies of the mushrooms or mycelium?**
A: Thank you for your question about Critical Immune Defense.  Our product was developed by some of the top Formulation Scientists and Biomolecular Scientists and it is safe, and effective.   In response to your question, the mushrooms are from the mycelial biomass, except for the Reishi Mushrooms, for which we do not have that information. 
Give Critical Immune Defense a try.  We offer a 30-day money-back guarantee.  Your cat or dog will thank you!
Sincerely,
Pet Wellness Direct

**Q: So where is the ingredient list? I cannot find one.**
A: Dear Moe -- If you scroll down on the Amazon page towards the bottom you will find the back label with all the ingredients.  Just in case you are not able to see it, here are the ingredients: 
Active Ingredients per 5 cc Scoop (equals 1 teaspoon): 
A Proprietary Blend of Turkey Tail Mushroom (with Polysaccharopeptide content not less than 38%. Peptide content not less than 20%), Reishi Mushroom, Shiitake Mushroom, and Maitake Mushroom  1,330 mg,
 Milk Thistle 70 mg, 
Calcium Ascorbate (Vitamin C) 68 mg, 
White Turmeric Root Extract 42 mg, (with total White Curcuminoids not less than 25%. Six times more bioavailable than standard turmeric.), 
Coenzyme Q-10 1.4 mg, 
Selenium 0.025 mg, 
Vitamin 1300 IU, Vitamin E (D-alpha-tocopheryl acetate) 40 IU.  
Inactive Ingredients: Brewer’s Yeast, Flaxseed, Natural Flavorings, Rice Bran.

We feel that Critical Immune Defense is the absolute best all-natural immune booster for pets, and we are very proud of our team of Formulation Scientists, Biomolecular Scientists, and sourcing experts that help to create this incredible product.  

Give our product a try.  We offer a 30-day money-back guarantee.
Most sincerely,
Pet Wellness Direct 
Customer Support

**Q: Is the turkey tail just the "fruiting" part or does it include the rooting part too?**
A: Thank you for your question about Critical Immune Defense.  Our product has been helping so many dogs and cats, and we’re very proud of the results.

Regarding your questions, we use a water-based extract process as we’ve found this gives us the best consistency and effectiveness.  The ratios do vary based on the mushrooms and the batch.  As a reference point, our hero mushroom in Critical Immune Defense is a very special Turkey Tail mushroom, and that ratio is 20:1.  So that means we use 20 pounds of the whole fruiting body mushrooms to derive one pound of extract powder.

We hope that helps, and feel free to let us know any other questions.

**Q: Are these mushroom grown on wood or grains?**
A: Our mushrooms are of the highest quality to maintain the specifications and standardization of Polysaccharides, Peptides and other nutrients.  They are grown via liquid culture cultivation process in an enclosed stainless-steel tank (also known as a bio-reactor).  The bio-reactor is partially filled with water and filled with nutrients that are usually a mixture of grains such as non-GMO soybeans, yeast and glucose.  That is how the mushrooms are grown.  We hope this information helps, and you give Critical Immune Defense a try.  Your pet will thank you!

## Customer Reviews

### ⭐⭐⭐⭐⭐ I AM BACK TO BUY MORE!
*by C***R on August 9, 2024*

Update: We have only one bottle of powder left, so I'm reordering. I still have my grand-dog, Gus, on this supplement, and he is still running and chasing the ball during play time. My son is a firm believer in this product, and so am I. I have my younger female dogs on it as well. It is costly, but when I consider eventual vet bills that might be prevented if dogs have this stuff all their lives, I prefer to keep them healthy now so we can avoid some of the absurdly expensive health issues later in life. I can't seem to leave a vet's office without a three-hundred-dollar bill, and that is for basically nothing. Anything serious can be one or two thousand or much higher. It strikes me as being smarter to try to prevent serious issues for as long as we can, and in the meantime, our three dogs are happy, healthy, and enjoying a good playtime with the ball every day. At mealtime, they don't hesitate to eat, and if we didn't get all the powder mixed in well with their food, they lick the bowls clean, getting every last bit of the supplement. After eating, they circle around to see if another dog left any traces of anything in the bowl, and if one misses some of this supplement powder, they lick it up. So it doesn't taste icky to my dogs. I researched the ingredients and am thinking about finding a human version of this stuff. I think the company has done a stellar job of researching what will actually help our dogs--and I know there are human supplements, made of approximately the same stuff, that reviewers rave about. I'm 76, but who knows? If I get the same nutrients, maybe I'll be more energetic as well and help chase that darned ball! First post: I got this, despite the price, just to see. My son has a seven-year-old Aussie who was no longer wanting to chase the ball, who stood back and just didn't seem to care about playing anymore with our two younger dogs. It was so sad to see! He is still so young. I remembered reading about Critical Immune Defense and seeing good reviews. So, despite the cost, I decided to order some. I gave my grand-dog, Gus, his three scoops (he's a larger dog than my girls, so they only get two) on his food per meal for three days. (I did mention to my son that I was doing so. It is his dog, after all.) So we sailed along for three days, and all of a sudden, my grand-dog, Gus, began bursting forward to chase the ball and play. He was like a puppy again, all excited and racing around. It made my heart swell, because I was thinking, "That Stuff is actually Working!" My son said nothing. So, I thought, okay, fine. I can do without spending all that money on snake poison, even though I believed I was seeing a huge change in my grand-dog, Gus. My thought was, "I saw a placebo effect. I convinced myself, so I believed in the hype." My son didn't mention seeing a difference. So, hello, the stuff is expensive. I decided not to buy anymore. I'm not an idiot. So a few days later, my son calls. (We live on the same property, so our dogs all eat together.) "Mom, are you still giving Gus his supplement?" I thought I had messed up, because I wasn't giving him anything. I was, like, WHAT supplement? My son was, like, that stuff that started making him play like a puppy again! He was very upset that I had stopped giving his dog the CID. He would have been eagerly willing to continue the supplement at his own cost and trouble! The difference in the dog was huge. I popped back, saying that he'd never said a word about how it changed Gus. Why would I continue giving it to him? The stuff is costly! (I hope the company can shave away at their overhead to reduce the cost of product. ) Bottom line, this stuff DOES work! It isn't about buying it and only thinking it works. It truly does, and our Gus is suddenly running and playing like a much younger dog. It has given him a new lease on life. I have decided to also give it to my two younger dogs, hopefully as a preventative supplement. And, hello, I'm researching to find a human-grade supplement with mostly the same ingredients. I could stand a boost energy to make me feel better, too!

### ⭐⭐⭐⭐⭐ Healthy pets
*by M***N on January 29, 2026*

Very good product for my pets.

### ⭐⭐⭐⭐⭐ Critical Immune Defense a supplement that works!
*by T***. on January 6, 2026*

This stuff works! I give this to my German Shepherd Heidi for her cyst growths . They were the size of a quarter and large enough to see . She had three. One completely went away while the other two are almost completely gone but has taken longer. I did not have her diagnosed so I don't know what the difference is between them but all I know is that this has and is removing them.

## Frequently Bought Together

- Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract - 30-Day Supply
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*Product available on Desertcart Slovakia*
*Store origin: SK*
*Last updated: 2026-03-19*