--- product_id: 258199059 title: "Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets" brand: "life extension" price: "€ 35.86" currency: EUR in_stock: true reviews_count: 5 category: "Life Extension" url: https://www.desertcart.sk/products/258199059-life-extension-optimized-folate-l-methylfolate-supports-heart-and-brain store_origin: SK region: Slovakia --- # 1700 mcg bioactive 5-MTHF folate Supports cognitive & neurotransmitter health Maintains healthy homocysteine for heart Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets **Brand:** life extension **Price:** € 35.86 **Availability:** ✅ In Stock ## Summary > 💡 Elevate your heart & mind with the folate upgrade you can’t afford to miss! ## Quick Answers - **What is this?** Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets by life extension - **How much does it cost?** € 35.86 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.sk](https://www.desertcart.sk/products/258199059-life-extension-optimized-folate-l-methylfolate-supports-heart-and-brain) ## Best For - life extension enthusiasts ## Why This Product - Trusted life extension brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Trusted Brand Legacy:** Life Extension’s proven quality with 4.7-star rating from 3,600+ users - • **Science-Backed Efficacy:** Formulated based on 40+ years of research for maximum absorption - • **Dual Brain & Heart Support:** Clinically linked to maintaining cognitive function and cardiovascular health - • **Bioactive Folate Powerhouse:** 1700 mcg of 5-MTHF, up to 7x more bioavailable than folic acid - • **Non-GMO & Gluten-Free Purity:** Clean, vegetarian formula crafted with premium ingredients ## Overview Life Extension Optimized Folate delivers 1700 mcg of metabolically active 5-MTHF folate per vegetarian tablet, supporting healthy homocysteine levels linked to cardiovascular and cognitive health. This non-GMO, gluten-free supplement offers superior bioavailability compared to standard folic acid, ensuring efficient nutrient absorption. Backed by over four decades of scientific research and trusted by thousands, it’s designed for adults seeking to optimize brain and heart wellness with a clean, potent formula. ## Description Folate helps maintain homocysteine levels within the normal range, which promotes cardiovascular health. And it also supports neurotransmitter synthesis — which in turn helps maintain cognitive abilities. However, not everyone has sufficient activity of the enzyme required to convert folate to its biologically active form, 5-methyltetrahydrofolate, or 5-MTHF. That’s why each vegetarian tablet of Optimized Folate provides 1,700 mcg of the bioactive 5-MTHF form of folate which is up to 7 times more bioavailable than ordinary folic acid Review: Excellent product,at a great price. It arrived in great packaging, it arrived exactly on time , there is no damage, product is in date, it had no odor. Not beneficial for energy. The item absorbes well. No known side effects. The idea of this medication is to take when you need support for cardiovascular and cognitive health and maintaining healthy homocysteine levels. Review: The quality is great. They work for moods and energy. ## Features - BIOLOGICALLY ACTIVE FOLIC ACID — Our Optimized Folate formula promotes both cardiovascular and cognitive health with 1700 mcg of folate in the form of 5-MTHF (L-Methylfolate), the metabolically active form of folic acid. - WHY FOLATE? – Maintaining normal levels of homocysteine, a metabolic byproduct, is associated with heart and brain health. Folate, a B vitamin, helps maintain homocysteine levels already within normal range. However, not everyone can efficiently convert folate to its biologically active form. Our formula provides 5-MTHF, so you don’t have to. - HEART & BRAIN-FRIENDLY NUTRIENT – Because folate helps inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular biomarker. Since healthy homocysteine levels have been associated with cognitive health, getting enough folate is especially crucial for individuals who want to maintain brain health. - INGREDIENTS MATTER - Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are non-GMO, gluten-free, and manufactured in the USA—and a Certificate of Analysis is available for every product we produce. - LIVE YOUR HEALTHIEST LIFE - For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach, and that rigorous scientific research is the path to get us there. Our formulations are created using the ingredients and dosages used in the studies that inspired them, ensuring that maximum bioavailability and efficacy is achieved. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00UD0IPYU | | ASIN | B00UD0IPYU | | Age Range Description | Adult | | Allergen Information | Gluten Free, Non-GMO | | Best Sellers Rank | #22,676 in Health ( See Top 100 in Health ) #229 in Vitamin B Supplements | | Brand Name | Life Extension | | Color | ... | | Container Type | Bottle | | Customer Reviews | 4.7 4.7 out of 5 stars (3,667) | | Customer reviews | 4.7 4.7 out of 5 stars (3,667) | | Diet Type | Gluten Free | | Dosage Form | Tablet | | Flavor | Unflavored | | Global Trade Identification Number | 00737870193913 | | Is Discontinued By Manufacturer | No | | Item Dimensions | 5.3 x 5.3 x 9.5 centimeters | | Item Form | Tablet | | Item Nype Name | L-Methylfolate Supplement | | Item Weight | 50 g | | Item model number | 01939 | | Manufacturer | Life Extension | | Manufacturer | Life Extension | | Manufacturer Part Number | 01939 | | Material Type Free | Gluten Free | | Model Name | VITAMIN_Life Extension | | Model Number | 01939 | | Number of Items | 1 | | Primary Supplement Type | Folate as (6S)-5-Methyltetrahydrofolate, calcium salt | | Product Benefits | Anti-Aging & Longevity, Brain Health, Heart Health | | Product Dimensions | 5.31 x 5.31 x 9.47 cm; 49.9 g | | Special Ingredients | microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, silica, vegetable stearate, stearic acid. | | Specific Uses For Product | Heart | | Supplement Formulation | Multi-Supplement | | UPC | 737870193913 | | Unit Count | 100 Count | ## Product Details - **Brand:** Life Extension - **Diet type:** Gluten Free - **Flavour:** Unflavored - **Item form:** Tablet - **Primary supplement type:** Folate as (6S)-5-Methyltetrahydrofolate, calcium salt ## Images ![Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets - Image 1](https://m.media-amazon.com/images/I/71vf+u6dkiL.jpg) ## Questions & Answers **Q: It says 1700 mcf DFE of folate, but how of that is actual folic acid equivalent?** A: Hello, We apologize for any confusion. At the end of August of 2020, we updated our Optimized Folate supplement facts section. The amount of folate was updated from 1,000 mcg to 1,700 mcg based on updated FDA labeling guidelines. This change is a result of what the FDA has defined as dietary folate equivalents (DFE). They determined that 0.6 mcg of (6S)-5-methyltetrahydrofolate, calcium salt is equal to 1 mcg DFE. They have also determined that one mcg of naturally occurring folate is equal to one mcg DFE. Their rationale is that this accounts for the greater bioavailability (6S)-5-methyltetrahydrofolate, calcium salt compared to naturally occurring folate. The change to 1,700 mcg in this product allows us to deliver the desired potency in terms of DFE. **Q: What is the expiration date?** A: The expiration date on mine is 7/20/2023, but I bought it over 3 months ago. I have no idea what the expiration date will be on the bottle you’re buying. **Q: Is this Metafolin?** A: Metafolin is a trademarked name for the active form of folate, known as methylfolate. While Optimized Folate doesn't utilize this specific brand, it does include L-Methylfolate. **Q: Is any component of your usa manufactured product sourced from china or india?** A: It's been a very long time since I purchased this product. I no longer have the container and have consumed all of the product. That said, I have since switched to Folic Acid 800 mcg made in Austin Texas and available on Amazon. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Review *by D***. on 25 April 2026* Excellent product,at a great price. It arrived in great packaging, it arrived exactly on time , there is no damage, product is in date, it had no odor. Not beneficial for energy. The item absorbes well. No known side effects. The idea of this medication is to take when you need support for cardiovascular and cognitive health and maintaining healthy homocysteine levels. ### ⭐⭐⭐⭐⭐ Review *by C***N on 30 April 2026* The quality is great. They work for moods and energy. ### ⭐⭐⭐⭐⭐ Review *by J***A on 2 March 2026* I use in conjunción with Vit. B12 3 times a week M W F ## Frequently Bought Together - Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets - Life Extension TMG 500 mg – Trimethylglycine Supplement – Encourages Healthy Homocysteine Levels – Gluten-free – Non-gmo – Vegetarian – 60 Liquid Vegetarian Capsules - Life Extension Neuro-Mag Magnesium L-Threonate, Magnesium L-threonate, Memory Health, Quick Thinking, Cognitive Health Support, Vegetarian, Non-GMO, 90 Vegetarian Capsules --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.sk/products/258199059-life-extension-optimized-folate-l-methylfolate-supports-heart-and-brain](https://www.desertcart.sk/products/258199059-life-extension-optimized-folate-l-methylfolate-supports-heart-and-brain) --- *Product available on Desertcart Slovakia* *Store origin: SK* *Last updated: 2026-05-16*