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🐕✨ Elevate your pet’s skin game with vet-approved, fast-acting freshness!
Douxo S3 SEB Dog Seboregulating Shampoo features 0.5% Ophytrium to soothe and hydrate irritated skin while controlling excess sebum, dandruff, and odors. Clinically proven to deliver visible results in 7 days, it is the #1 vet-recommended topical brand for managing seborrheic skin conditions in dogs and cats. This sulfate- and paraben-free formula ensures safe, effective, and professional-grade skin care for your furry companion.




















| Asin | B09478VXZP |
| Best Sellers Rank | #106 in Dog Shampoos |
| Date First Available | May 5, 2021 |
| Item Model Number | D98620E |
| Manufacturer | Douxo S3 |
| Package Dimensions | 7.52 x 3.46 x 2.13 inches; 1.32 pounds |
User
The Shampoo That Turned My Greaseball Into a Show Dog
I bought Douxo S3 Seb Shampoo for my bulldog, who had developed a persistent case of oily seborrhea that made him smell like a forgotten gym sock and look like he’d been dipped in fryer grease. We’d tried everything—medicated wipes, antifungal sprays, even vet-prescribed shampoos that smelled like chemical warfare. Nothing worked for more than a day. Then came Douxo.The first thing I noticed was the texture: thick, creamy, and easy to lather. It didn’t run off his coat like water on wax. I massaged it in and let it sit for the recommended 10 minutes, which he tolerated surprisingly well thanks to the mild scent—clean, almost herbal, and not remotely medicinal. After rinsing, his coat felt softer, less greasy, and the usual sour odor was gone. Not masked—gone.By the third wash, the transformation was undeniable. His skin wasn’t flaking, his fur had a matte finish instead of a slick sheen, and he stopped scratching like he was auditioning for a flea circus. Even the vet was impressed. The shampoo didn’t just clean—it recalibrated his skin. The Ophytrium ingredient seems to work like a skin whisperer, calming inflammation and restoring balance without stripping natural oils.I’ve since used it on my other dog, a golden retriever with seasonal dandruff, and it worked just as well. The bottle lasts longer than expected, and the formula rinses clean without leaving residue. It’s become a staple in our grooming routine, and I now recommend it to every pet owner I meet at the dog park.
User
It got rid of her doggy dandruff
The vet recommended this shampoo because our newly adopted pup had some dandruff. It worked wonders for her. It may seem expensive, but it was worth it. The only thing I do wish is that it had a better smell. It doesn't smell bad at all, it just doesn't smell good either. More like there isn't much of a smell. I prefer a noticeable fresh, clean smell after bathing my doggy. But, it did work great.
User
Great Product!
Great shampoo for dogs with Seborrhea! Doesn't take a lot. Just put a small amount on your dog then wet it and work it into the fur. Gets rid of the greasy looking and dandruff fur. I had a GS so had to bathe her twice a week in the beginning.
User
Works Great
My vet told me to use this for my dog while she is recovering from a very bad allergy issue that we have been trying to get under control for over a year that caused her skin to become very thick and scaley; to the point her fur could not grow in properly. I have been using this on her over the past two months and her coat has started to come back in so nicely. She still has a few rough scaley spots, but I am hopeful that she will have her coat back fully in a few more months.
User
“Helps remove excess sebum, oils and flaky skin buildup.”
My canine dermatologist recommend this product. A bit more expensive than most but works great on dogs with allergic reactions secondary to buildup of environmental issues and oily skin and hair. (Make sure to rub it in through the hair to scrub the skin.)
User
Great product, shipping is terrible!
I want to start out by saying this product is absolutely amazing for my pup with a genetic skin condition. However, they need to figure out how to ship the product better. The last several times it leaked all over everything that it was shipped with. I attached pictures but the only offer was to return the item and be refunded when I desperately need this item for my dog and no chat option. This shampoo is expensive which I am ok with if it works but not to waste all over the packaging!
User
Cleared problem immediately
Recommended by the vet for a skin issue on our doodle’s tail. Cleared up very quickly with only 2 uses. Didn’t notice a smell, odor or fragrance that would have made anyone allergic. Good lather. Rinses off easily.
User
This shampoo is a great help!
This shampoo hasn’t “fixed” my Golden’s stinky, oily, itchy, flaky coat, but it has helped SO much!First of all, it’s so gentle and soothing that I can use it more often than normal shampoo to take care of his stink without making the itch and flakiness worse, which is a win on its own. But a major plus is that I really think it has helped with improving the overall health of his skin and coat. He’s so much less itchy after a bath now than before (typically it’s the opposite) and the scent of the shampoo really takes away that stinky dog smell. He still gets stinky and oily quickly, especially compared to other dogs that don’t have this problem (seriously, you can smell him after just 5-6 days), but it’s better than what it was (the freshly bathed, clean dog smell used to only last 3 days tops before, so any extension is a win). Also, no more hot spots since starting this shampoo! To clarify, he never had a huge issue with hot spots like some dogs do. At its worst, we would find one or two a month just starting, but they never got really inflamed like I know some dogs’ do, so if your dog really struggles maybe take that with a grain of salt. This product is so gentle and soothing though, I know it won’t make skin irritations worse.We wet his fur throughly and work this shampoo in really well, starting with the areas that get the most oily, flaky, and itchy. We do avoid the face with this, never really going past the ears. Then we let it set for the entire 10 minutes. We like to give him a lick mat while he waits. Then we rinse, leaving his problem areas for last. We can give him a bath every two weeks with this shampoo (we never would have done more than every 3 wks with a normal shampoo, even though with the smell, he could use a bath every week).
User
Na
Na
User
Duoxo
Es un shampoo para la piel de mi perrita que padece de ictiasis
User
Love the smell
It’s amazing smell and make my dogs smell so good after the shower. It makes the fur soft too which I love.
Trustpilot
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