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Winner of the 2023 PROSE Award for Excellence in Biological and Life Sciences and the 2023 Chautauqua Prize! Named a New York Times Notable Book and a Best Book of the Year by The Economist , Oprah Daily, BookPage, Book Riot, the New York Public Library, and more! In The Song of the Cell , the extraordinary author of the Pulitzer Prize-winning The Emperor of All Maladies and the #1 New York Times bestseller The Gene “blends cutting-edge research, impeccable scholarship, intrepid reporting, and gorgeous prose into an encyclopedic study that reads like a literary page-turner” ( Oprah Daily ). Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christened them “ cells. ” The discovery of cells—and the reframing of the human body as a cellular ecosystem—announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer’s dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumonia—all could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies. Filled with writing so vivid, lucid, and suspenseful that complex science becomes thrilling, The Song of the Cell tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. Told in six parts, and laced with Mukherjee’s own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimate—a masterpiece on what it means to be human. “In an account both lyrical and capacious, Mukherjee takes us through an evolution of human understanding: from the seventeenth-century discovery that humans are made up of cells to our cutting-edge technologies for manipulating and deploying cells for therapeutic purposes” ( The New Yorker). Review: A Symphony of Science, History, and Personal Narrative - In a landscape saturated with scientific literature that often feels inaccessible to the layperson, "The Song of the Cell: An Exploration of Medicine and the New Human" stands out as a beacon of clarity and engagement. This book is not just for the scientifically inclined; it's a compelling read that draws in a diverse audience, including those who may not typically gravitate toward science. One of the book's most striking features is its ability to engage readers who are not science-oriented. The author employs a storytelling approach, using analogies, vivid descriptions, and relatable examples to explain complex scientific concepts. You don't need a background in biology or medicine to appreciate the groundbreaking developments discussed in this book; the author ensures that the material is accessible and, more importantly, fascinating for all. The book serves as a gateway into the world of new developments in medicine, from editing T cells to personalized treatments. It's not just a snapshot of where we are now; it's a narrative that pulls you into a future where medicine could be radically different and far more effective than what we've known. The excitement of what's possible is palpable on every page, making you eager to see these advancements come to fruition. As someone who enjoys history, I particularly appreciated the book's historical perspective on medicine. The author takes us on a journey through time, exploring how our understanding of medicine has evolved and how past discoveries have paved the way for today's innovations. This historical lens adds depth to the narrative and provides a fuller understanding of how far we've come—and how far we still have to go. What sets this book apart from others in the genre is the way the author weaves in personal experiences. Whether it's a family history of a particular illness or firsthand accounts of working in a lab, these personal touches make the narrative more relatable and engaging. It's not just a book about science; it's a book about people, making it all the more compelling. Overall, "The Song of the Cell: An Exploration of Medicine and the New Human" is a masterful blend of science, history, and personal narrative. It's a book that will not only educate you but also inspire a sense of wonder and optimism about the future of medicine. Whether you're a science enthusiast or a history buff, or even if you're neither, this book has something to offer you. Highly recommended for anyone looking to expand their understanding of what medicine has been, what it is, and what it could one day become. Review: Another great book by Siddhartha Mukherjee - Having already read “The Emperor of All Maladies” and “The Gene”, it was an easy decision to also read “The Song of the Cell”. Oddly, the desertcart “Product Details” refers to this book as “History of Biology & Nature”, “Medical History” and “Ancient Early Civilization History”. What a terrible and misleading description for this book. Certainly, this book, like the author’s previous two books, talks about some of hypotheses proposed by medieval scholars and about many of the experiments performed by past scientists and researchers. So, yes, the book includes some of the history of cell research (which I liked, by the way). But, more importantly, the author uses this history as a means to have the reader slowly gain a more and more complete and detailed understanding of the structure and behavior of the cellular world that makes up the human body. There are two major parts to the book (though several other aspects of the cell are also covered). The first part focuses on science’s developing knowledge of cell. What are the different parts that make up each cell? How do cells extract energy from the body so they can perform their basic function? How do cells eliminate waste given their double-walled structure? Many, many such questions are covered in this book. And, of course, there are still many more questions for which we do not yet have an answer. The second part of the book talks about the cooperative way that cells in specific organs can work together to accomplish that organ’s function. How do heart cells work together to make the heart act as a beating pump? How do the brain’s synapses function? Some of the other organs covered include bones (and bone growth), pancreas, liver, kidney and blood (and immune system). Unfortunately, my two-part description is sadly oversimplified. There is just so much diverse, interesting information in this book; and it is so well written. My review simply cannot do proper justice to the book itself. Some miscellaneous, unrelated thoughts that especially stuck with me. [ ] At one point, when describing one specific aspect of science’s increasing understanding of the cellular biology, the author pointed out that, although he wrote just a single paragraph on that aspect, it actually took scientists about two decades to arrive at their understanding. [ ] There are single-celled animals, but of course humans are an integration of a huge variety of specialized cells. The story of multi-celled biology is the development of these specialized cells. [ ] The portions of this book hardest for me to try and comprehend and absorb had to do with how cells actually function. The discussions on proteins and enzymes and peptides were a bit beyond me as organic chemistry is a subject I’ve never read about before. [ ] In this book, the author names many researchers. But he doesn’t just give their names. Typically, there is a brief comment on their physical appearance and personality as well. I viewed this as the author’s way of honoring those pioneers, peers and mentors who also have devoted their lives to the science of the cell. Bottom Line: “The Emperor of All Maladies” was an exceptional book. Still, both “The Gene” and this book, “The Song of the Cell”, are great reads, too.
| Best Sellers Rank | #60,465 in Books ( See Top 100 in Books ) #6 in Cell Biology (Books) #14 in History of Medicine (Books) #64 in History of Civilization & Culture |
| Customer Reviews | 4.7 out of 5 stars 3,115 Reviews |
Y**E
A Symphony of Science, History, and Personal Narrative
In a landscape saturated with scientific literature that often feels inaccessible to the layperson, "The Song of the Cell: An Exploration of Medicine and the New Human" stands out as a beacon of clarity and engagement. This book is not just for the scientifically inclined; it's a compelling read that draws in a diverse audience, including those who may not typically gravitate toward science. One of the book's most striking features is its ability to engage readers who are not science-oriented. The author employs a storytelling approach, using analogies, vivid descriptions, and relatable examples to explain complex scientific concepts. You don't need a background in biology or medicine to appreciate the groundbreaking developments discussed in this book; the author ensures that the material is accessible and, more importantly, fascinating for all. The book serves as a gateway into the world of new developments in medicine, from editing T cells to personalized treatments. It's not just a snapshot of where we are now; it's a narrative that pulls you into a future where medicine could be radically different and far more effective than what we've known. The excitement of what's possible is palpable on every page, making you eager to see these advancements come to fruition. As someone who enjoys history, I particularly appreciated the book's historical perspective on medicine. The author takes us on a journey through time, exploring how our understanding of medicine has evolved and how past discoveries have paved the way for today's innovations. This historical lens adds depth to the narrative and provides a fuller understanding of how far we've come—and how far we still have to go. What sets this book apart from others in the genre is the way the author weaves in personal experiences. Whether it's a family history of a particular illness or firsthand accounts of working in a lab, these personal touches make the narrative more relatable and engaging. It's not just a book about science; it's a book about people, making it all the more compelling. Overall, "The Song of the Cell: An Exploration of Medicine and the New Human" is a masterful blend of science, history, and personal narrative. It's a book that will not only educate you but also inspire a sense of wonder and optimism about the future of medicine. Whether you're a science enthusiast or a history buff, or even if you're neither, this book has something to offer you. Highly recommended for anyone looking to expand their understanding of what medicine has been, what it is, and what it could one day become.
F**R
Another great book by Siddhartha Mukherjee
Having already read “The Emperor of All Maladies” and “The Gene”, it was an easy decision to also read “The Song of the Cell”. Oddly, the Amazon “Product Details” refers to this book as “History of Biology & Nature”, “Medical History” and “Ancient Early Civilization History”. What a terrible and misleading description for this book. Certainly, this book, like the author’s previous two books, talks about some of hypotheses proposed by medieval scholars and about many of the experiments performed by past scientists and researchers. So, yes, the book includes some of the history of cell research (which I liked, by the way). But, more importantly, the author uses this history as a means to have the reader slowly gain a more and more complete and detailed understanding of the structure and behavior of the cellular world that makes up the human body. There are two major parts to the book (though several other aspects of the cell are also covered). The first part focuses on science’s developing knowledge of cell. What are the different parts that make up each cell? How do cells extract energy from the body so they can perform their basic function? How do cells eliminate waste given their double-walled structure? Many, many such questions are covered in this book. And, of course, there are still many more questions for which we do not yet have an answer. The second part of the book talks about the cooperative way that cells in specific organs can work together to accomplish that organ’s function. How do heart cells work together to make the heart act as a beating pump? How do the brain’s synapses function? Some of the other organs covered include bones (and bone growth), pancreas, liver, kidney and blood (and immune system). Unfortunately, my two-part description is sadly oversimplified. There is just so much diverse, interesting information in this book; and it is so well written. My review simply cannot do proper justice to the book itself. Some miscellaneous, unrelated thoughts that especially stuck with me. [ ] At one point, when describing one specific aspect of science’s increasing understanding of the cellular biology, the author pointed out that, although he wrote just a single paragraph on that aspect, it actually took scientists about two decades to arrive at their understanding. [ ] There are single-celled animals, but of course humans are an integration of a huge variety of specialized cells. The story of multi-celled biology is the development of these specialized cells. [ ] The portions of this book hardest for me to try and comprehend and absorb had to do with how cells actually function. The discussions on proteins and enzymes and peptides were a bit beyond me as organic chemistry is a subject I’ve never read about before. [ ] In this book, the author names many researchers. But he doesn’t just give their names. Typically, there is a brief comment on their physical appearance and personality as well. I viewed this as the author’s way of honoring those pioneers, peers and mentors who also have devoted their lives to the science of the cell. Bottom Line: “The Emperor of All Maladies” was an exceptional book. Still, both “The Gene” and this book, “The Song of the Cell”, are great reads, too.
P**K
great cell biology book
A remarkable review of cell biology by this wonderful writer. With all the praise in so many reviews, I do not find anything new to say. However, I was expecting to see a shorter version with more poetry and less rigorous science, with song used in its title. Interdependence or interconnecting signals might support the song idea which is a bit confusing (may be, it sells the book better). References to parallel findings in ecology I found attractive, but less compelling.Nonetheless, for biologists and many physicians it is an unmatched source of highly updated information and research guidance.
L**S
Packed with Science and Personal Stories
The author, Siddhartha Mukherjee, when he finished the “Emperor of all Maladies” didn’t think he had another book in him. However, he followed up with a book called the “Gene” which had science, a history of science but also very personal revelations. And then the book “Song of the Cell” was published. Mukherjee has a very distinct style of combining hard science with history and personal stories that make his books on science very relatable. I can’t say that it is easy reading. The parts of the book that are science, not history not personal stories, read more like a textbook. There is so much information in this book as well as others that I could probably reread this book on multiple occasions and learn more. Or, you could consider just going back to a particular section to review that one subject. All this being said Mukherjee is a remarkable author, scientist, and oncologist. He is extremely thoughtful and looks at a scientific issue from almost every angle and perspective. This is quite uncommon and very helpful in having a full picture of not only the science, but how it applies to the human condition.
M**A
GREAT READ
As a STEM girly, this book was an incredible read! I would recommend this to all my STEM lovers and non-science readers as well. It is not too science dense for folks who may not be familiar with biological processes.
M**N
The Miracle of Human Biology
Mukherjee explains the role of cells and their diversity in human life and its disorders with compelling cases and research history.
P**S
Awesome to the n
I remember my experience reading Dr. Mukherjee’s “Emperor of all Maladies”. It was an awesome read. This was even more so. After reading this (I can’t say finishing because the story goes on to meet the challenges of understanding the human body and developing treatments that respond to its awesome complexities), I am even more in awe of what nature has created, the wonder that is human existence. As just one of this species, I have a new appreciation for the miracle that inhabits me. This is also scary because I now realize how many things are going right for me to be alive and to have lived for 80 years. And yes, it heightens my sense of fragility, how easily things could go wrong and bring my life to an end, likely with the period of dysfunction and pain that others have experienced. I am not particularly religious but I I think I will be more thankful now for each additional day that I live. Awesome also describes Dr. Mukherjee’s skill in writing about this subject in a way that I feel I can somewhat understand what he is describing, a subject that is far beyond my expertise. He not only writes with great skill but also with an ability to get into the shoes, the limited understanding, of his readers. Yes, he inevitably uses difficult technical medical terms, but he explains each of these. And he gives lucid descriptions of the research and the researchers who made the discoveries, persisted through failures along the way. And yet more so, I appreciate the real patients who he describes caught in these discoveries with results that sometimes don’t lead to better lives and sometimes do. I recommend this book to anyone who has the curiosity to know what goes on inside of them.
H**N
Fancinating book
Fascinating book, great read.
H**S
Boog
Good book. No page holders on soft cover, but keep it intact and it'll last
A**R
Magnífico Libro
Trata temas científicos de manera amena y con lenguaje no muy técnico, lo que facilita su lectura.
L**H
Très bon livre
Très bon livre
Z**S
Enlightening and Thought Provoking
A couple of years ago I read Mukherjee’s 2010 book: The Emperor of All Maladies: A Biography of Cancer, and was impressed by his ability to both explain very complex biological processes while at the same time grounding explanations with historical or real world personal stories. Similarly, The Song of the Cell: An Exploration of Medicine and the New Human, is a fascinating exploration into cell biology and how it is integral in our existence. Mukherjee is rightly known for his ability to bridge the gap between scientific research and storytelling to help explain complex concepts. An ability that he again demonstrates with this work. The book takes readers on an enlightening journey from early myths and beliefs regarding the intricacies of human biology to the recent advancements in medical science that are shaping our understanding of the human body. With his signature clarity and lyrical prose, he paints a vivid picture of the complex symphony within and between our cells, unravelling some of the secrets that lie within and their profound implications for medicine. The author infuses the text with his own experiences and reflections from medical practice and research, creating I think, an intimate connection between the author and the reader. His humility and genuine curiosity is evident, making the scientific journey feel personal and relatable. Given the very broad ambition of this book inevitably there are sections I found either too technical or just too detailed. This aside, Mukherjee’s strength is the ability to make complex scientific concepts accessible, while also delving into the deeper medical and ethical questions that arise from the progress of medical science. This book will leave readers informed, inspired, and with a profound appreciation for the awe-inspiring symphony that unfolds within the cells of our bodies and is the reason I rated it 5 stars.
J**R
Thought provoking book
I really enjoyed this review of the cell. As a health professional it helped to review the workings of the cell the basic building block of life. The book was very thought provoking and gave us a snapshot of where cell biology is headed and the incredible potential it promises. A very good and worthwhile read.
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