Fisetin Supplement - 100mg of Bioactive Flavnonols, 60 Count (Bioflavonoid Polyphenols Supplement Similar to Apigenin, Luteolin, and Quercetin) Aging Support Senolytic by Double Wood

I’ve been taking this 100mg bioactive Fisetin supplement every morning on an empty stomach, and I’m excited about its potential benefits. I started taking it after learning that fisetin is primarily found in strawberries, and I also try to include them in my diet.The capsules are easy to take, and I appreciate the quality of this supplement. While it’s too early to tell the long-term effects, I’m hopeful about its anti-aging and cognitive support benefits.Would love to see a higher dose per serving option in the future, but overall, I’m pleased with this product!

This is a very promising new supplement.Fisetin is a senotherapeutic that extends health and lifespan. It may also have general uses to reduce inflammation and reduce allergic reactions. Quercetin is another bio-flavonoid that can mitigate histamine intolerance and mast cell reactions associated with histamine intolerance and may work well in combination with Fisetin.There are a lot of pretty exciting recent studies about the potential therapeutic effects of Fisetin. I will quote one:"A panel of flavonoid polyphenols was screened for senolytic activity using senescent murine and human fibroblasts, driven by oxidative and genotoxic stress, respectively. The top senotherapeutic flavonoid was tested in mice modeling a progeroid syndrome carrying a p16INK4a-luciferase reporter and aged wild-type mice to determine the effects of fisetin on senescence markers, age-related histopathology, disease markers, health span and lifespan. Human adipose tissue explants were used to determine if results translated. Of the 10 flavonoids tested, fisetin was the most potent senolytic. Acute or intermittent treatment of progeroid and old mice with fisetin reduced senescence markers in multiple tissues, consistent with a hit-and-run senolytic mechanism. Fisetin reduced senescence in a subset of cells in murine and human adipose tissue, demonstrating cell-type specificity. Administration of fisetin to wild-type mice late in life restored tissue homeostasis, reduced age-related pathology, and extended median and maximum lifespan."

Somehow I stumbled across fisetin right here on Amazon. I can't even remember what I was originally shopping for, but I am grateful I encountered this. I have had a brutal sleep disorder for over a year - waking up every night after about 2 hours of sleep with inability to return to sleep. My mind was turning into a shambles, and my ability to focus and remember things was laughable. I'd pretty much made peace with this, but then I stumbled across Fisetin, and I can't believe the impact it had. I won't go so far as to say everybody will be wowed, but for me personally the impact was life changing and just about straightened me back out, at least a huge difference versus where I'd ended up at. Now to keep this real, I take quite a few supplements and experiment with all kinds of different stuff, especially with this sleep problem. From neurotropic hacks to Ashgwanda root, and berberine and everything else under the sun. And frankly, while I waste a good fistful of dollars every month, I can't tell that any of them really do anything. So I stepped into this one with a bit of skepticism, but the impact was almost instant, and seems to last.

I found this product of high quality and reasonably priced. As for clinical effects, the benefits would seem to be with longer term use. Preventing cataracts, cardiovascular, cancer treatment, memory enhancement are among animal studied benefits! I found no liver enzyme elevations at the suggested dose.

First, let me say that I was not compensated in any way for this review. The company did follow up with me after receiving my order. Nice to know some companies still understand the importance and value of customer service. EXCELLENT customer service. They have a devoted customer now! Here’s my review of the product:I received my order promptly. This supplement was suggested by my doctor as a way to remove senescent cell accumulation. Pulse dosing - 1500 mg per day, two consecutive days per month. This will be a long term supplement for me. As such, I haven’t noticed any negative or positive results yet. However, I was pleased to discover that even with such a high dose, I had no negative side effects. Supplements or medicine often cause upset stomach for me but I didn’t experience any negative side effects at all. The capsules are very thin and have no flavor making them easy to swallow.

I first heard of this supplement when I was researching the best supplements to add to my diet at the onset of COVID 19.I have been very pleased with the results and the positive benefits I have experienced since I began taking this 4 months ago.It has assisted in my mental clarity and this company has one of the highest senolytic activity. This senolytic activity removes senescent cells that are damaged and have lost their ability to reproduce.I trust Fisetin and specifically Double Wood Supplements to deliver a quality product that will assist in the anti aging process while keeping my immune system operating at high performance.

I may be doing Sudoku puzzles faster from shear practice but fisetin might help as I've noticed that you MUST NOT take it before bedtime or you'll stay away as your brain doesn't want to sleep. Take in the morning or afternoon.WARNING: I noticed an increase in impatience or irritability an hour or two after taking and then searched the internet and found others experiencing similar feelings. Perhaps because there is a stimulating effect? But you get used to it after a while and realize the cause.As for fisetin's senolytic properties you'll have to get back to me in 20 years or so to see if it does work as research indicates. I suggest you do a search and look at the articles published at reputable sites on fisetin such as the National Institute of Health, Nature, the Salk Institute and many others with more studies added regularly.