How are these different from digestive enzymes? I already take digestive enzymes that don’t seem to be helping me any longer. Are these stronger?

I order these every month for my Mom. She was diagnosed with pancreatic insufficiency and needs these enzymes to digest food properly. These are great if you need higher doses, particularly for the Lipase (which helps digest fats.) My Mom also uses the Pure Lipase supplements with these for extra added help digesting fats (that is her main problem and what causes her the most digestive problems.) My mom's doctor recommended these because her prescription for Creon enzymes (basically the same thing) had a $400 per month copay (ridiculous!) and these actually work much better for her (especially after she adds in the Lipase supplement.) These are superior to Creon at a MUCH better price.

Is it enteric coated?

Based on the ingredients listed, i dont think they're enteric coated. However i can attest to this supplement's effectiveness. My Mom-in-law and had serious digestion problems throughout years of chronic illness, and a few years ago she got severe pancreatitis and had the majority of her pancreas removed. Everything got worse after that. She couldn't eat, she was losing weight like crazy, very sickly. She was put on Creon, which helped incredibly. Unfortunately she couldn't keep affording the absolutely ridiculous $1500/mo it costed, so she had to stop.. And everything went downhill after that again. No other enzyme blends helped her get this problem under control. I started doing research and found out about Pure Encapsulations Pancreatic enzyme formula and noticed the blend was VERY similar to Creon. (except its $80 for a huge bottle! Grrrr pharmaceutical industry!) and we got her a bottle and within a few days she started feeling so much better! Was able to start enjoying food again. Many of her GI issues subsided. She said it made her feel like she was on the Creon again. And she's been much better ever since. I can't thank this company enough for this incredible product! And that's my two cents!

Could you tell me what the mg and USP units for this particular product for the 5 contents?

capsule 500mg: Lipase-17,500 usp units, protease-110,000 usp units, amylase-120,000 usp units. The formulation is very close to Zenpep prescription. I use this when I hit the doughnut hole in my medicare due to the extremely high cost of Zenpep. I have noticed no difference in the effectiveness of the product. Recommended by a naturopath friend.

It doesn't list corn on the ingredients and says it is NON-GMO so probably since most of the corn..or all of it is GMO. It works for me

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Reviews

O**J

Better than Creon

Purchased for my wife when my insurance plan stopped supporting her prescription for Creon (pancralipase). Purchasing out of pocket would have been $1200! So I did some research and tried this. She loves it and says it is more effective than Creon.

5.01.2026

L**O

Good product

My husband just went through 6 months of testing to discover it problems with his digestive system is Pancreatic Enzyme Insufficiency. It was recommended by his doctor to take Creon and was given a sample amount of them to try. They didn't set well with him and were way to expensive. Through a lot of research, and recommendations from others online we decided to give these a try. They seem to be working and have change his enzyme level by 50 %. It is the same 3 enzyme's that are in Creon but at different doses. He is on the mend and is playing with the dosage to accommodate his system and needs. I would recommend this product.

8.11.2025

S**L

Helps me digest yood and stops sugar cravings

I have been ordering this from a vitamin shop and they are expensive but I found this smaller bottle at a good price! These pills help me digest food better and helped me when I was on Keto diet! I think they really helped me not crave carbs and sugar. My doctor recommended this brand

5.09.2025

A**R

Digestive Enzymes

Giving it a Four star because I think its helping with my EPI. I've ordered a second bottle to continue with this process. I can't afford the prescription drugs for EPI with insurance at $1000/mo. So I would recommend giving it a try.

26.12.2025

M**L

Great supplement

10.12.2025

R**N

great product

This suppliment was recommended ro me by an herbalist in Florida a couple years ago I was taking a perscription pancreatic enzyme before that that didnt really work. This one works for me and works well.

14.10.2025

D**S

Handy capsule

Works good

17.01.2026

W**W

It works

This supplement really works. My my stomach and bowels are extremely better normal. I take a probiotic, but I really think that I needed this supplement for the longest.

12.09.2025

ASIN	B0016X92JK
Best Sellers Rank	#20,114 in Health & Household ( See Top 100 in Health & Household ) #77 in Multi-Enzyme Nutritional Supplements #2,380 in Diet & Sports Nutrition
Customer Reviews	4.5 4.5 out of 5 stars (725)
Date First Available	March 30, 2008
Department	unisex-adult
Item model number	PE6
Manufacturer	Pure Encapsulations
Product Dimensions	3.8 x 2.3 x 1.8 inches; 2.4 ounces

Pancreatic Enzyme Formula - Digestive Enzymes for Digestion - Strengthens Gut Health* - Targeted Delivery Capsules - Gluten Free & Non-GMO - 60 Capsules

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