

⏳ Elevate your energy & wellness game with time-release precision!
21st Century Niacinamide 500 mg Prolonged Release Tablets deliver a steady supply of vitamin B3 to support energy metabolism, skin health, and nervous system function. With 110 vegan, gluten-free, and non-GMO tablets free from artificial additives, this trusted supplement is crafted in a cGMP-certified facility ensuring purity and potency. Ideal for professionals seeking sustained vitality and clean nutrition, it offers flexible dosing to fit your lifestyle.













| ASIN | B004SCKMQS |
| Age Range Description | Adult |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #8,547 in Health & Household ( See Top 100 in Health & Household ) #10 in Vitamin B3 (Niacin) Supplements #983 in Sales & Deals |
| Brand Name | 21st Century |
| Color | No Color |
| Customer Reviews | 4.6 out of 5 stars 5,198 Reviews |
| Diet Type | Vegan |
| Dosage Form | Tablet |
| Flavor | Unflavored |
| Global Trade Identification Number | 00740985225509 |
| Item Dimensions | 2 x 3 x 4 inches |
| Item Form | Tablet |
| Item Height | 4 inches |
| Item Weight | 500 Milligrams |
| Manufacturer | 21st Century |
| Model Name | av2023-21st Century-mg prolonged release tablets-5f0674d8 |
| Number of Items | 1 |
| Primary Supplement Type | Vitamin-b |
| Product Benefits | Helps convert food into energy and helps maintain skin, digestive and nervous systems |
| Special Ingredients | Gluten Free |
| Specific Uses For Product | Digestive,Skin,Energy |
| UPC | 740985225509 |
| Unit Count | 110 Count |
H**R
time-release Niacinamie + time-release melatonin... Great sleep FINALLY!
So, wow. Fellow strugglers of proper sleep: perhaps you got to here after learning about the "Healthy Sleep Formula" created by Steve Gibson, as I did. If not, and sleep is an issue for you, I highly recommend you google "Healthy sleep formula" to get to the page on grc .com. That guy has a HUGE following. So much so that when he developed his version 2.0 of the sleep formula and recommend a specific brand of Niacinamide, it sold out everywhere. I knew right then that there must be something to this formula of his. Then he popped back with an update stating that this brand was officially recommended after it had been tested out. I would have never thought that Niacinamide (the amide of nicotinic acid (vitamin B3 / niacin)) + melatonin could be such a magic sleep cocktail. And trust me, at this point I have tried a lot of different supplements. I suffer from the kind of insomnia where you can easily go to sleep, but not remain asleep (sleep-maintaining insomnia disorder)... tossing and turning, rarely getting into deep sleep/REM and waking up everyday feeling pretty exhausted. What a waste of time, honestly. I have been on a long road of finding ways to improve this issue through healthy means, trying my best to avoid actual sleeping pills. Things would work for a bit... then no longer be effective and it would be this endless chase for the next sleep fix. But this formula offered me something new: a combination of 2 time-release pills taken together. It addressed my exact needs. And I am here to say, it works. It WORKS LONG-TERM. I have been doing this formula of time-release Nicinamide and time-release melatonin for several weeks now and its amazing the energy I have now. Many days I wake up about 10-15 minutes before my scheduled alarm for work, have much more vivid dreams, have no issue getting out of bed and out the door, actually feel like going to the gym on my lunch break instead of taking a car nap...it's put me on a great healthy schedule overall and feeling top of my game. I actually look forward to bedtime now. If you do Steve's formula, you have to figure out what is best for you. I will state that I am not a sensitive person and typically need higher dosages of things. In my experimenting I have found that 1250mg of Niacinamide + the 1mg melatonin works best for me to sleep through the night without crossing over into groggy-ville. It is one reason why I like this brand being a lower dosage of 500mg, so I can easily up 1/2 and full dosages cutting the pills. It was very much a goldilocks situation... 1 is too little... 2 is too little... 3 IS TOO MUCH IM IN A HAZE... 2.5 is just right :D So thats my story of Niacinamide and how it's solved my sleep-maintaining insomnia. Pretty amazing, I can't fully believe it yet. Just in case you are wondering the breadcrumb trail of how I got here... it went: friend told me about GABA... and combining with taurine to be more effective. I researched GABA and stumbled on a "sleep hacking through biochemistry" blog... read about all these things to help get you into sleep faster and more lasting, and replacing 5-HTP with tryptophan (but it mentioning a high tryptophan diet might not be healthy so being careful not to use constantly)...blah blah read some reviews on the tryptophan I was getting and mentioning Steve Gibson's healthy sleep formula. His 1st generation formula used a handful of all those aforementioned things till he developed the 2nd gen one. Glad I jumped on board after that point! Its cheap and super effective.
S**T
Very very very good.
The first day I took this I got a lot of energy for about an hour then I seemed to have sort of "crashed". But that was only the first day. Since then I've taken it every morning and it's been incredible. I have more energy and my joints don't hurt. I'd say I'm even in a better mood because of it. I highly recommend it.
P**1
For my Needs it's Priced Right, Works, and Provides some Peace of Mind.
Inexpensive, pill isn't too big to be inconvenient to swallow (unless you really require a small pill). Took this instead of the extremely expensive prescription drug my doctor recommended, and while it only provides about 1/6th the benefit (based on actual bloodwork by my doctor) it provides it at 1.5% of the cost while giving me some peace of mind.
A**R
Not dead yet.
I’m not dead yet, so it’s working, I guess. Skin doctor recommended, and this is least expensive version I have found.
I**L
Gentle & Long-Lasting Niacinamide Support
I’ve been taking 21st Century Niacinamide 500 mg Prolonged Release Tablets (110‑count) daily for a few weeks, and I’m pleasantly surprised by how consistently my skin and energy feel. The prolonged-release formula means each tablet releases evenly throughout the day, so I don’t experience any of the flushing or irritation I’ve had with other niacin supplements. Just one tablet in the morning with breakfast is all it takes to keep things steady. Aside from mild skin-brightening and hydration support, I’ve noticed my energy levels feel steadier—no typical midday dips or fog. The bottle is large and lasts a long time, and the tablets are easy to swallow. Overall, it’s a solid, budget-friendly choice for anyone seeking the benefits of niacinamide without the usual side effects or needing frequent doses.
S**H
Easy to swallow
I take this daily. It is essential for me.
B**Y
No improvement
I have not noticed any improvement.
D**A
Good
Good
Trustpilot
4 days ago
1 month ago